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Al Gemelli Polyclinic in Rome the first case of this in Italy has been successfully performed uterine transposition, an innovative technique to temporarily move the uterus and ovaries higher in the abdomen, protecting them from radiation during chemotherapy for pelvic cancer, and then repositioning them after treatment, preserving fertility and the possibility of future pregnancies. 

A multidisciplinary team performed the complex surgery, which allowed the patient to undergo lifesaving treatment and preserve her fertility, without denying her the possibility of becoming a mother in the future.

What is Uterine Transposition?

This technique aims to preserve fertility in young women who must undergo radiotherapy in the pelvic area.

During the operation, the uterus and ovaries are temporarily moved to a safe area, outside the radiation field, but, at the end of the therapy, the organs are returned to their original position, maintaining the ability to conceive and carry a pregnancy. 

Il Gemelli Polyclinic in Rome It is the first center in Italy to perform this procedure, starting with a clinical study (“DISPLUT trial”) to evaluate its efficacy and safety. Only subsequently did a multidisciplinary team made up of gynecological oncologists, radiotherapists, and surgeons perform the surgery.

Why was the surgery performed?

Facing aggressive cancer therapies can unequivocally compromise the ovaries and uterus and drastically reduce the egg reserve and uterine capacity.

Thanks to this revolutionary technique, a concrete prospect of future motherhood is offered to patients who would otherwise have to give it up. 

Epidemiological data in fact demonstrate that the incidence of tumors in young people under the 40 years is on the rise (+2.6% per year), especially in women, which is also associated, in Europe, with a increased mortality (+ 49 %).

The Gemelli Polyclinic is the first center in Italy and among the few in the world to offer uterine transposition to preserve fertility and is conducting a prospective clinical study (“DISPLUT trial”) to evaluate its efficacy, safety and obstetric outcomes.  

To send reports of eligible patients

To submit reports regarding patients who are potential candidates for uterine transposition at the Gemelli Polyclinic, please contact: ppgad@pucrs.br. 

Gemelli Hospital in Rome: first case of uterine transposition in Italy last edit: 2026-01-19T12:52:59+01:00 da laracalogiuri

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